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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CLCNKA
All Species:
9.39
Human Site:
T681
Identified Species:
18.79
UniProt:
P51800
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P51800
NP_001036169.1
687
75285
T681
K
K
A
I
S
N
L
T
N
P
P
A
P
K
_
Chimpanzee
Pan troglodytes
XP_525229
687
75266
T681
K
K
A
I
S
N
L
T
N
P
P
A
P
K
_
Rhesus Macaque
Macaca mulatta
XP_001091784
740
81203
K680
P
G
S
Q
G
Q
S
K
A
G
D
P
C
L
R
Dog
Lupus familis
XP_544547
687
75469
T681
K
K
A
I
S
N
L
T
N
P
P
A
P
K
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUB7
687
75650
I681
K
K
A
I
S
T
L
I
N
P
P
A
P
K
_
Rat
Rattus norvegicus
Q06393
687
75551
I681
K
K
A
I
S
T
L
I
N
P
P
A
P
K
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_425749
696
76448
Q683
P
A
G
T
L
G
E
Q
G
L
R
R
A
I
E
Frog
Xenopus laevis
NP_001079308
689
76782
E683
K
E
M
K
K
A
I
E
D
L
A
N
P
K
_
Zebra Danio
Brachydanio rerio
NP_956676
693
75983
E687
K
E
M
K
K
I
I
E
K
M
A
K
E
V
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGH7
1193
133629
N1101
R
K
A
I
E
D
I
N
S
N
S
F
V
P
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P60300
763
83497
H739
R
H
D
F
M
P
E
H
I
L
G
L
H
P
S
Baker's Yeast
Sacchar. cerevisiae
P37020
779
87664
Y741
L
R
F
K
R
I
K
Y
R
E
V
H
G
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
81.3
87.4
N.A.
82.5
83.2
N.A.
N.A.
60
61.9
43.5
N.A.
27.4
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
86.2
93
N.A.
90.8
91.2
N.A.
N.A.
73.5
78.5
62.1
N.A.
39.8
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
100
N.A.
85.7
85.7
N.A.
N.A.
0
21.4
7.1
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
85.7
85.7
N.A.
N.A.
0
42.8
21.4
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.4
43.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
50
0
0
9
0
0
9
0
17
42
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
9
0
9
0
0
0
0
% D
% Glu:
0
17
0
0
9
0
17
17
0
9
0
0
9
0
9
% E
% Phe:
0
0
9
9
0
0
0
0
0
0
0
9
0
0
0
% F
% Gly:
0
9
9
0
9
9
0
0
9
9
9
0
9
0
0
% G
% His:
0
9
0
0
0
0
0
9
0
0
0
9
9
0
0
% H
% Ile:
0
0
0
50
0
17
25
17
9
0
0
0
0
9
0
% I
% Lys:
59
50
0
25
17
0
9
9
9
0
0
9
0
50
9
% K
% Leu:
9
0
0
0
9
0
42
0
0
25
0
9
0
9
0
% L
% Met:
0
0
17
0
9
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
25
0
9
42
9
0
9
0
0
0
% N
% Pro:
17
0
0
0
0
9
0
0
0
42
42
9
50
17
9
% P
% Gln:
0
0
0
9
0
9
0
9
0
0
0
0
0
0
0
% Q
% Arg:
17
9
0
0
9
0
0
0
9
0
9
9
0
0
9
% R
% Ser:
0
0
9
0
42
0
9
0
9
0
9
0
0
0
9
% S
% Thr:
0
0
0
9
0
17
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
9
0
9
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
59
% _